A short answer for those who are looking fast

Heartburn is a symptom, not a disease. It may be caused by GERD, hypersensitive esophagus, or functional heartburn. That is why antacids and omeprazole do not help everyone. For the treatment to work, it's important to understand the cause first.

Heartburn seems like a simple complaint. But it is with her that people come to the gastroenterologist who have been drinking one drug after another for years — and nothing changes. Let's find out why this is happening.


Heartburn, reflux, and GERD are not the same thing.

It is important to understand this right away, because the whole treatment depends on it.

Heartburn is a burning sensation behind the sternum. Just a symptom. Reflux is a process where the contents of the stomach are thrown into the esophagus. It also happens in perfectly healthy people, for example, after a hearty dinner. GERD is already a disease: regular symptoms, damage to the esophageal mucosa, or complications.

If the symptom is really acid-dependent, drugs that reduce acidity usually help. But if there is another mechanism behind the "heartburn" (for example, functional heartburn or impaired motility), then omeprazole, which reduces acidity, provides only partial relief or does not work at all. It's not that omeprazole is weak. It's just that there's no target for him in this case.

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Why does the esophagus react to casting

There are two key mechanisms behind the symptoms.

The first is a violation of the anti—reflux barrier. The lower esophageal sphincter normally does not let the contents of the stomach back up. If it works worse, reflux occurs. Hernia of the esophageal orifice of the diaphragm, obesity, and pregnancy contribute to this.

The second is delayed esophageal clearance. Even if the cast has occurred, the esophagus must quickly "clear itself" of it — with the help of peristalsis, saliva and gravity. The longer the acid is in contact with the mucosa, the more severe the symptoms.

At the same time, the intensity of burning does not always coincide with the severity of reflux: sometimes a slightly acidic cast causes severe pain, and a significant acid load is almost not felt. Therefore, not only the properties of the reflux are important, but also the sensitivity of the esophagus itself.


Three different reasons — one feeling

GERB. The classic pattern is a burning sensation behind the sternum and a feeling of acid in the mouth, especially after eating, when bending over or lying down. The risk is higher with overweight, herniated diaphragm, late and heavy dinners. The nocturnal symptoms are particularly significant: in the horizontal position, the clearance of the esophagus slows down, and even a small episode of reflux lasts longer. By the way, sleeping on the left side reduces nocturnal acid load — this has been confirmed by research.

Hypersensitive esophagus. There are reflux symptoms, but they are within the normal range — it's just that the esophagus reacts to them too sharply. If we draw an analogy with a fire alarm: the stimulus is small, but the alarm is like in a large fire. The symptoms in humans are real, even if there is no pathological reflux according to the examination.

Functional heartburn. There is a burning sensation, but there is no pathological reflux — and the symptoms are not time-related to episodes of withdrawal. Gastroscopy shows no damage. It's like a fire alarm that goes off without smoke or fire. That is why drugs that reduce acidity are often ineffective in this condition.


When heartburn is no longer just "drinking an antacid"

There are symptoms that do not require a change of medication, but a comprehensive examination. These are the so-called "red flags":

  • difficulty swallowing
  • unintentional weight loss
  • anemia
  • vomiting
  • pain when swallowing
  • Symptoms first appeared after the age of 50
  • treatment has no effect with an adequate course.

If at least one of these points concerns you, do not delay the consultation.


What actually helps

Reduce the load on the anti-reflux barrier. If you are overweight, reducing it significantly reduces the symptoms. Late and heavy dinners worsen the situation, especially with nocturnal complaints. A raised headboard works if symptoms occur while lying down. It is important to lift the head end of the bed or use a wedge—shaped cushion, rather than just adding a pillow.

Nutrition: there is no universal blacklist of foods. Coffee, chocolate, tomatoes, mint, and fatty foods can trigger symptoms, but the reaction is individual. It's more practical not to exclude everything, but to find your triggers.

Antacids and alginates they are suitable as an ambulance for rare heartburn. They are not able to cure GERD, but they quickly relieve the symptoms.

Proton Pump Inhibitors — the basis of treatment is if heartburn is typical and recurs regularly. It is important to understand: PPIs do not eliminate the cast itself, they only make the reflux less aggressive. Therefore, with functional heartburn or hypersensitive esophagus, they work much worse.

If the treatment does not help — you should not endlessly change drugs in the hope of finding a "stronger one." At this stage, it is more important to review the diagnosis itself. Heartburn can be caused by functional disorders, eosinophilic esophagitis, drug damage to the esophagus, and other conditions.

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Why you shouldn't ignore chronic heartburn

The same burning sensation behind the breastbone does not mean the same cause. Heartburn can be caused by GERD, hypersensitive esophagus, or functional heartburn, and the treatment varies. Therefore, if antacids do not help or the symptoms recur regularly, it makes sense to figure out exactly what is happening, and not just change the drug.


Make an appointment for a gastroenterologist's consultation in Dubai You can use WhatsApp or by phone at the Kandinsky Clinic. The doctor will assess the condition of the skin, prescribe tests, if necessary, which can be done in the Kandinsky Clinic's own laboratory, and select the optimal treatment strategy.


The material has been prepared for educational purposes and does not replace a full-time consultation with a doctor. The decision on diagnosis and treatment should be made jointly with a specialist.


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Heartburn: Why pills don't always help | Kandinsky Clinic